Pillar 10
Longevity
The cutting edge of aging science.
The 9 Hallmarks of Aging
- Genomic instability
- Telomere attrition
- Epigenetic alterations
- Loss of proteostasis
- Mitochondrial dysfunction
- Cellular senescence
- Stem cell exhaustion
- Altered intercellular communication
- Deregulated nutrient sensing
Interventions Being Studied
- Rapamycin — mTOR inhibition
- Metformin/Berberine — AMPK activation
- NAD+ precursors — Cellular energy
- Senolytics — Clearing zombie cells
- Caloric restriction mimetics
What Works Now
Exercise, sleep, nutrition, stress management, and social connection remain the most proven interventions. Dont chase drugs—master the basics first.